WHICH POTENCY PILL SUITS ME BEST?
Causes and treatment methods of ED
Erectile dysfunction rarely leads
to another illness in most patients, and therefore, this state of health is not
taken very seriously by health insurance companies. Impotence can have various
causes, but if it is not caused by harmful involvement of the working
conditions, the person concerned usually has to bear the full cost of the
treatment himself.
The causes of impotence can be
natural reasons such as old age or stress in the relationship, or other
illnesses can cause them. Still, often it is unhealthy lifestyle habits that
are considered the leading cause of erectile dysfunction. The most common
methods of treating male sexual dysfunction include oral medicines (called
PDE-5 inhibitors), topical medicines, mechanical aids such as vacuum pumps or
penis rings, hormone therapy, and surgical interventions. The least invasive
and, therefore, the most popular of all these treatment methods are oral pills Fildena 100 and vigora.
Effect of phosphodiesterase 5 inhibitors
At the moment, only oral erectile
drug vigora 100 is used, which are based
on one of the four phosphodiesterases 5 inhibitors - Viagra Sildenafil Citrate,
Cialis Tadalafil, Levitra Vardenafil or Avanafil found. These PDE-5 inhibitors
inhibit the cGMP-degrading enzyme phosphodiesterase, which usually contributes
to the rapid termination of the erection, and thus leads to a more permanent
enlargement of the blood vessels in the erectile tissue of the penis and a
longer duration of the erection.
It goes without saying that these
results can only be felt with simultaneous sexual stimulation. Strangely
enough, the most common side effects do not include the feared adverse impact
on blood pressure but complaints such as headache, facial flushing,
indigestion, nasal congestion, back pain, and visual disturbances.
The four PDE-5 inhibitors
sildenafil, Vardenafil, Tadalafil, and Avanafil mostly differ from each other
only in the speed at which the effects occur, their duration, and compatibility
with other ingested substances. Sildenafil Fildena is considered among the four to be the most
effective erectile dysfunction in all age groups, Tadalafil as the
longest-acting PDE-5 inhibitor, Vardenafil is the most sustainable alternative
that is prescribed for older men who also have to use some other medications,
with Avanafil being the fastest onset of action has.
Sildenafil Citrate
Sildenafil Citrate was the first
PDE-5 inhibitor to be approved for the treatment of male erectile dysfunction
in 1998 under the trade name Viagra. Sildenafil acts very quickly (the effect
starts after about 30 minutes), is highly effective in both younger and older
patients, and can also be prescribed off-label for the treatment of sexual
dysfunction in female patients.
Sildenafil is the oldest, most
commonly prescribed, and most widely prescribed PDE-5 inhibitor for impotence
treatment, and therefore its side effects and interactions are well known and
thoroughly documented. In addition to Viagra, this drug is the only active
ingredient in various generic branded erectile medications such as Fildena 150mg, Kamagra, Cenforce 100,
Suhagra, and Vigora used.
The disadvantages of Sildenafil
include the weak effect while eating large and fatty meals and its relatively
short duration of action. In addition to the treatment of erectile dysfunction,
Sildenafil Citrate has also been approved under the trade name Revatio since
2006 for the treatment of idiopathic pulmonary arterial hypertension.
You must take Sildenafil about 30 minutes to 1 hour before you
plan to engage in sexual activity. The effect of a dose lasts about 4 hours.
Tadalafil
Tadalafil is a drug that has been
approved since 2003 under the trade name Cialis for the treatment of erectile
dysfunction in male patients. It works similarly to Sildenafil. The effects
start even faster than with Sildenafil and often last up to 36 hours. This
makes Tadalafil the longest acting PDE-5
inhibitor. Another advantage is that it is well-tolerated with alcohol and full
meals. Therefore, this sexual enhancer is suitable for men who want to eat
complete and drink alcohol before sexual intercourse and want to pursue several
sexual experiences in succession within 24-36 hours. Similar to Sildenafil
Citrate, there are also soft chewable tablets and jellies, i.e.,
stomach-friendly and faster-acting forms of delivery of this active ingredient,
which allow the patient to avoid any adverse effects on the digestive tract.
Tadalafil is out Cialis also used in branded generics like Apcalis Oral Jelly,
Tadacip and Tadalis Sx. At the end of 2012, Tadalafil was also approved for the
treatment of the benign prostate syndrome.
It is recommended that you take Tadalafil about 15 minutes
before you plan to have sex. The effect of a dose can last up to 36 hours.
Vardenafil
Vardenafil was approved as a second
PDE-5 inhibitor under the trade name Levitra in March 2003 for the treatment of
sexual dysfunction in male patients. Its mechanism of action is very similar to
the above-mentioned PDE-5 inhibitors sildenafil and Tadalafil, and its duration
of action is practically identical to that of Sildenafil. Its most significant
advantage is its perfect compatibility with other medications. Therefore
Vardenafil is mainly prescribed for the elderly who also have to take
medications for the treatment of other health conditions regularly. The
essential interactions include those with nitrite-containing drugs or NO donors
and grapefruit juice. A disadvantage of Vardenafil can be called its slightly
weaker effectiveness compared to Sildenafil Fildena 50 mg and
Tadalafil, but, as with all other drugs, it depends on the individual patient.
Vardenafil is currently only marketed as Levitra.
Vardenafil should be taken about 1 hour before you plan to
engage in sexual activity. The effect starts in 15 to 60 minutes and usually
lasts 5 to 6 hours.
Avanafil
Avanafil is the youngest drug from
the PDE-5 inhibitor category used to address potency problems. This active
ingredient was only approved in Germany in 2013 but is not yet available in
some countries such as Switzerland. In Europe, this mono-preparation is known
under the trade name Spedra whereby the trade name Stendra used in North
America is known to many Germans. Avanafil (together with Tadalafil) has the
fastest onset of action among all PDE-5 inhibitors, its efficiency is very high
(about as high as that of the high-efficiency Sildenafil) and its half-life and
therefore its duration of action of over 6 hours (sometimes even up to 12)
Hours) lie between Sildenafil and Vardenafil on the one hand and the Tadalafil
on the other side. Studies have shown that although Avanafil has the same high
effectiveness as Sildenafil, the risk of a possible drop in blood pressure is
lower. Thus the drug Avanafil should be more tolerable.
Avanafil should be used 15-30 minutes before planned sexual
activity. The effect starts in about 15 minutes and will last for over 6 hours.
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